Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393944 | 0.87 | POLB (0.77) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL17372580 | 0.84 | POLB (0.73) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL30063430 | 0.84 | POLB (0.72) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11175842 | 0.84 | POLB (0.72) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL61187 | 0.83 | POLB (0.71) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL2486782 | 0.83 | POLB (0.70) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL10595800 | 0.82 | POLB (0.70) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL27825330 | 0.82 | POLB (0.70) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL12982918 | 0.82 | POLB (0.70) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL29739277 | 0.82 | POLB (0.69) | POLBALDH1A1LMNAGRM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662206-A1 | GSPT1 DEGRADER COMPOUNDS | Captor Therapeutics S.A. (PL) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024165577-A1 | GSPT1 DEGRADER COMPOUNDS | CAPTOR THERAPEUTICS S.A. (PL) | 2024-08-15 | — | — | WO | disclosed |
| WO-2024167423-A1 | GSPT1 DEGRADER COMPOUNDS | CAPTOR THERAPEUTICS S.A. (PL) | 2024-08-15 | — | — | WO | disclosed |