Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 3/20 | 0.60 |
| ▸ | PI4KA | P42356 | 1/20 | 0.60 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 18/20 | 0.48 |
| ▸ | MTOR | P42345 | 8/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029669 | 0.94 | PIK3CG (0.58) | PIK3CGPI4KAPIK3C3PIK3CAMTOR | |
| SCHEMBL31029565 | 0.90 | PIK3CG (0.61) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL30333788 | 0.90 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL31029570 | 0.90 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL30333401 | 0.89 | PIK3CG (0.60) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL31029734 | 0.89 | PIK3CG (0.60) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL31029531 | 0.88 | PIK3CG (0.65) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL31029588 | 0.88 | PIK3CG (0.64) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL31029657 | 0.87 | PIK3CG (0.57) | PIK3CGPI4KAPIK3C3PIK3CAMTOR | |
| SCHEMBL31029606 | 0.86 | PIK3CG (0.56) | PIK3CGPI4KAPIK3CAMTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145589-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2025-05-08 | — | — | US | disclosed |
| EP-4406948-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | Sichuan Huiyu Pharmaceutical Co., Ltd. (CN) | 2024-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145589-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | KRAS, NRAS, BRAF | PIK3CG 4/4885PI4KA 60/4885PIK3C3 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.