SCHEMBL31031216

SCHEMBL31031216

C=Cc1ccc2c(c1)nc1cc(N3CC(OCCOC4CCCCO4)C3)ccn12

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31031219 0.83
SCHEMBL31031238 0.83
SCHEMBL31031220 0.74
SCHEMBL31031233 0.74
SCHEMBL17888605 0.69 KDM4C (0.45) KDM4CL3MBTL1NPC1RAB9A
SCHEMBL26437703 0.68 HRH3 (0.46) KDM4CL3MBTL1NPC1RAB9A
SCHEMBL17931428 0.67 KMT2A (0.39) KDM4CL3MBTL1NPC1RAB9A
SCHEMBL17888523 0.67 MEN1 (0.42) KDM4CL3MBTL1NPC1RAB9A
SCHEMBL17888581 0.67 MEN1 (0.39) KDM4CL3MBTL1NPC1RAB9A
SCHEMBL17888570 0.67 MEN1 (0.39) KDM4CL3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658651-A1 NOVEL COMPOUNDS FOR TAU IMAGING Eli Lilly and Company (US) 2025-12-10 EP disclosed
WO-2024163546-A1 NOVEL COMPOUNDS FOR TAU IMAGING ELI LILLY AND COMPANY (US) 2024-08-08 WO disclosed