Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240706 | 0.81 | SCN9A (0.46) | SCN9AKCNH2SCN5AMAPK10GRM4 | |
| SCHEMBL3871509 | 0.81 | JAK2 (0.52) | SCN9AKCNH2SCN5AMAPK10GRM4 | |
| SCHEMBL6157207 | 0.78 | ABCG2 (0.50) | SCN9AKCNH2SCN5AMAPK10GSK3B | |
| SCHEMBL31031227 | 0.77 | SCN5A (0.43) | SCN9AKCNH2SCN5AMAPK10GRM4 | |
| SCHEMBL20074425 | 0.76 | CDK2 (0.60) | ROCK1EGFRERBB3CCNA2CDK2 | |
| SCHEMBL16926590 | 0.74 | SMARCA2 (0.46) | SCN9AKCNH2SCN5AMAPK10GRM4 | |
| SCHEMBL31240789 | 0.72 | ABL1 (0.48) | MAPK10GRM4HTR3EHTR3BHTR3A | |
| SCHEMBL16926594 | 0.72 | GRM4 (0.54) | SCN9AKCNH2SCN5AMAPK10GRM4 | |
| SCHEMBL16926547 | 0.70 | MEN1 (0.53) | MAPK10GRM4JAK2TYK2NPC1 | |
| SCHEMBL16926546 | 0.69 | JAK2 (0.51) | GRM4MAPTJAK2TYK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |