Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712946 | 1.00 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL21712985 | 0.89 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL22166240 | 0.89 | KLKB1 (0.44) | KLKB1 | |
| SCHEMBL21713085 | 0.81 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL31033212 | 0.81 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL21736676 | 0.80 | KLKB1 (0.60) | KLKB1 | |
| SCHEMBL31741510 | 0.80 | KLKB1 (0.60) | KLKB1 | |
| SCHEMBL21712947 | 0.79 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL20541004 | 0.79 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL21736656 | 0.79 | KLKB1 (0.49) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |