Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712975 | 1.00 | KLKB1 (0.78) | KLKB1 | |
| SCHEMBL21736710 | 0.85 | KLKB1 (0.84) | KLKB1 | |
| SCHEMBL22166247 | 0.85 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL21736722 | 0.84 | KLKB1 (0.84) | KLKB1 | |
| SCHEMBL31741522 | 0.83 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL22166232 | 0.83 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL21736758 | 0.83 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL31741470 | 0.82 | KLKB1 (0.93) | KLKB1 | |
| SCHEMBL21713008 | 0.82 | KLKB1 (0.93) | KLKB1 | |
| SCHEMBL21736716 | 0.81 | KLKB1 (1.00) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |