Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 16/20 | 0.61 |
| ▸ | RBP4 | P02753 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712970 | 1.00 | KLKB1 (0.61) | KLKB1RBP4DAO | |
| SCHEMBL21712973 | 0.91 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL31033230 | 0.79 | KLKB1 (0.54) | KLKB1RBP4 | |
| SCHEMBL21712956 | 0.79 | KLKB1 (0.54) | KLKB1RBP4 | |
| SCHEMBL21736678 | 0.78 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL21747135 | 0.78 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL21713054 | 0.78 | KLKB1 (0.64) | KLKB1RBP4 | |
| SCHEMBL31033191 | 0.78 | KLKB1 (0.64) | KLKB1RBP4 | |
| SCHEMBL23769361 | 0.76 | KLKB1 (0.54) | KLKB1RBP4 | |
| SCHEMBL23769264 | 0.75 | KLKB1 (0.53) | KLKB1RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |