Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625637 | 0.86 | MEN1 (0.37) | MEN1NPC1RAB9AKMT2ACHRNB2 | |
| SCHEMBL3447574 | 0.86 | MEN1 (0.39) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL25233759 | 0.81 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL9908423 | 0.78 | MEN1 (0.39) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL7129953 | 0.78 | CYP1A2 (0.37) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL15373732 | 0.77 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL19746512 | 0.77 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL3316247 | 0.77 | MEN1 (0.41) | MEN1NPC1RAB9AKMT2AOPRK1 | |
| SCHEMBL20860351 | 0.77 | — | — | |
| SCHEMBL24521730 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175905-A1 | DIMER COMPOUNDS | Kesmalea Therapeutics Limited (GB) | 2024-08-29 | — | — | WO | disclosed |