SCHEMBL31033488

SCHEMBL31033488

C[13c]1n[13c]2[13cH][13cH][13cH][13c](C)[13c]2[nH]1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 5/20 0.56
TNKS2 Q9H2K2 1/20 0.46
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
AHR P35869 1/20 0.41
KIF11 P52732 1/20 0.39
AR P10275 1/20 0.39
ADORA3 P0DMS8 1/20 0.38
DAO P14920 1/20 0.38
DDO Q99489 1/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353892 1.00 PARP1 (0.56) PARP1TNKS2NPC1RAB9ASMN1; SMN2
Bromide SCHEMBL5318093 0.98 PARP1 (0.55) PARP1TNKS2NPC1RAB9ASMN1; SMN2
Phosphoric Acid SCHEMBL30514699 0.89 PARP1 (0.51) PARP1TNKS2NPC1RAB9ASMN1; SMN2
Succinic Acid SCHEMBL28523841 0.85 PARP1 (0.47) PARP1TNKS2RAB9ASMN1; SMN2ALDH1A1
Isoxazole SCHEMBL28611399 0.83 PARP1 (0.43) PARP1TNKS2NPC1RAB9ASMN1; SMN2
Hydrochlorthiazide SCHEMBL11538086 0.82 PARP1 (0.42) PARP1TNKS2NPC1RAB9ASMN1; SMN2
SCHEMBL6368182 0.81 PARP1 (0.47) PARP1TNKS2NPC1RAB9ASMN1; SMN2
SCHEMBL5142221 0.79 PARP1 (0.59) PARP1TNKS2NPC1RAB9ASMN1; SMN2
SCHEMBL1013611 0.79 PARP1 (0.46) PARP1TNKS2NPC1RAB9ASMN1; SMN2
SCHEMBL9502126 0.79 PARP1 (0.44) PARP1TNKS2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114216982-B Vitamin B12Is a detection method of (2) 黑龙江飞鹤乳业有限公司 2024-08-09 CN disclosed