Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.63 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.63 |
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.63 |
| ▸ | GLP1R | P43220 | 1/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.63 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.63 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596175 | 0.88 | AVPR2 (0.72) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL15242148 | 0.85 | AVPR2 (0.75) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL12744541 | 0.84 | AVPR2 (0.73) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL582867 | 0.84 | AVPR2 (0.73) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL31108767 | 0.83 | AVPR2 (0.76) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL12744542 | 0.83 | AVPR2 (0.73) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL583090 | 0.82 | AVPR2 (0.74) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Hydrochloric Acid SCHEMBL583715 | 0.82 | AVPR2 (0.67) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL3240170 | 0.81 | AVPR2 (0.81) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL15790271 | 0.81 | AVPR2 (0.81) | AVPR2AVPR1AABCB11HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240309030-A1 | BENZAZEPINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | SHANGHAI SENHUI MEDICINE CO., LTD. (CN) | 2024-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240309030-A1 | BENZAZEPINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | AVPR2, AVPR1B, AVPR1A | AVPR2 1/4885AVPR1A 3/4885ABCB11 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.