Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 16/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034863 | 0.86 | HCRTR2 (0.49) | HCRTR2GPR119 | |
| SCHEMBL29666586 | 0.82 | HCRTR2 (0.64) | HCRTR2 | |
| SCHEMBL31034893 | 0.77 | HCRTR2 (0.48) | HCRTR2GPR119 | |
| SCHEMBL31034920 | 0.76 | HCRTR2 (0.51) | HCRTR2GPR119 | |
| SCHEMBL31034880 | 0.76 | HCRTR2 (0.53) | HCRTR2 | |
| SCHEMBL31034874 | 0.75 | HCRTR2 (0.46) | HCRTR2 | |
| SCHEMBL31034860 | 0.74 | KLK7 (0.40) | HCRTR2GPR119 | |
| SCHEMBL31035009 | 0.74 | HCRTR2 (0.46) | HCRTR2 | |
| SCHEMBL30674779 | 0.73 | HCRTR2 (0.34) | HCRTR2GPR119 | |
| SCHEMBL31034897 | 0.72 | HCRTR2 (0.41) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658660-A1 | MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF | Jazz Pharmaceuticals Ireland Limited (IE) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160822-A1 | MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-08-08 | — | — | WO | disclosed |