Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036001 | 0.88 | NOTUM (0.59) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL28383838 | 0.85 | NOTUM (0.59) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL19538866 | 0.83 | MAPT (0.59) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL21379454 | 0.83 | HTR2C (0.60) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL29757934 | 0.81 | HTR2B (0.58) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL13808316 | 0.81 | HTR2B (0.58) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL31035856 | 0.80 | HTR2C (0.52) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL12110170 | 0.80 | HTR2B (0.64) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL19538872 | 0.79 | HTR2C (0.56) | NOTUMCYP3A4HTR2BKDM4EMEN1 | |
| SCHEMBL1148605 | 0.79 | HTR2B (0.62) | NOTUMCYP3A4HTR2BKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |