Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147622 | 1.00 | MEN1 (0.77) | MEN1KMT2ANAAACASP2TDP1 | |
| SCHEMBL8162651 | 1.00 | MEN1 (0.77) | MEN1KMT2ANAAACASP2TDP1 | |
| SCHEMBL8162613 | 0.98 | MEN1 (0.81) | MEN1KMT2ANAAACASP2TDP1 | |
| SCHEMBL311295 | 0.91 | — | — | |
| SCHEMBL21765846 | 0.91 | MEN1 (0.94) | MEN1KMT2ANAAACASP2ALDH1A1 | |
| SCHEMBL9259257 | 0.91 | MEN1 (0.94) | MEN1KMT2ANAAACASP2ALDH1A1 | |
| SCHEMBL11758762 | 0.91 | MEN1 (0.94) | MEN1KMT2ANAAACASP2ALDH1A1 | |
| SCHEMBL17229157 | 0.88 | MEN1 (1.00) | MEN1KMT2ANAAACASP2ALDH1A1 | |
| SCHEMBL8209020 | 0.84 | MEN1 (0.81) | MEN1KMT2ANAAACASP2EPHX1 | |
| SCHEMBL10866272 | 0.84 | MEN1 (0.81) | MEN1KMT2ANAAACASP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |