Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 19/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256586 | 0.93 | SCN10A (0.48) | SCN10AOPRK1 | |
| SCHEMBL31037410 | 0.92 | SCN10A (0.47) | SCN10AOPRK1 | |
| SCHEMBL29256635 | 0.92 | SCN10A (0.47) | SCN10AOPRK1 | |
| SCHEMBL31037406 | 0.87 | SCN10A (0.45) | SCN10A | |
| SCHEMBL25389301 | 0.86 | SCN10A (0.60) | SCN10AOPRK1 | |
| SCHEMBL31163995 | 0.86 | SCN10A (0.60) | SCN10AOPRK1 | |
| SCHEMBL31343813 | 0.85 | SCN10A (0.62) | SCN10AOPRK1 | |
| SCHEMBL29256627 | 0.83 | SCN10A (0.53) | SCN10AOPRK1 | |
| SCHEMBL21905978 | 0.82 | SCN10A (0.63) | SCN10AOPRK1 | |
| SCHEMBL21906100 | 0.82 | SCN10A (0.60) | SCN10AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217344-A1 | NAV1.8 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2024-10-24 | — | — | WO | disclosed |
| CN-118324743-A | Nav1.8 inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-12 | — | — | CN | disclosed |