Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 19/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256692 | 1.00 | SCN10A (0.45) | SCN10APTGER4 | |
| SCHEMBL29256657 | 0.88 | SCN10A (0.47) | SCN10A | |
| SCHEMBL26608348 | 0.84 | SCN10A (0.47) | SCN10A | |
| SCHEMBL26615749 | 0.82 | SCN10A (0.47) | SCN10APTGER4 | |
| SCHEMBL31037432 | 0.80 | SCN10A (0.56) | SCN10A | |
| SCHEMBL29256640 | 0.80 | SCN10A (0.56) | SCN10A | |
| SCHEMBL31163991 | 0.80 | SCN10A (0.45) | SCN10A | |
| SCHEMBL31037406 | 0.80 | SCN10A (0.45) | SCN10A | |
| SCHEMBL25391058 | 0.79 | SCN10A (0.60) | SCN10A | |
| SCHEMBL31164003 | 0.79 | SCN10A (0.46) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324743-A | Nav1.8 inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-12 | — | — | CN | disclosed |