SCHEMBL31037656

SCHEMBL31037656

CCCCc1nc2c(N)nc3ccccc3c2n1CC1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.68
TLR8 Q9NR97 6/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037666 0.91 TLR7 (0.54) TLR7TLR8
SCHEMBL20647765 0.84 TLR7 (0.77) TLR7TLR8
SCHEMBL3864996 0.84 TLR7 (0.49) TLR7TLR8
SCHEMBL25919412 0.83 TLR7 (0.81) TLR7TLR8
SCHEMBL24859956 0.83 TLR7 (0.72) TLR7TLR8
SCHEMBL3868390 0.81 TLR7 (0.53) TLR7TLR8
SCHEMBL3866052 0.81 KDM1A (0.45) TLR7TLR8
SCHEMBL26756090 0.81 TLR7 (0.83) TLR7TLR8
SCHEMBL3867954 0.80 TLR7 (0.47) TLR7TLR8
SCHEMBL29475744 0.80 TLR7 (0.55) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024138157-A1 NOVEL IMIDAZOQUINOLINES WITH IMMUNOSTIMULATORY EFFECTS SYNOVO GMBH (DE) 2024-06-27 WO disclosed