Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29257192 | 1.00 | HPGD (0.46) | HPGDMGLLVNN1MEN1ALDH1A1 | |
| SCHEMBL24942619 | 1.00 | HPGD (0.46) | HPGDMGLLVNN1MEN1ALDH1A1 | |
| SCHEMBL30201327 | 0.91 | HPGD (0.49) | HPGDMGLLVNN1MEN1ALDH1A1 | |
| SCHEMBL31038239 | 0.91 | HPGD (0.49) | HPGDMGLLVNN1MEN1ALDH1A1 | |
| SCHEMBL24942621 | 0.83 | HPGD (0.52) | HPGDMGLLVNN1DDR1ADRA1A | |
| SCHEMBL24463672 | 0.80 | HPGD (0.52) | HPGDMGLLVNN1DDR1ADRA1A | |
| SCHEMBL24463716 | 0.79 | HPGD (0.56) | HPGDMGLLVNN1MEN1KMT2A | |
| SCHEMBL24942620 | 0.79 | HPGD (0.51) | HPGDMGLLVNN1DDR1ADRA1A | |
| SCHEMBL30201439 | 0.78 | HPGD (0.50) | HPGDMGLLVNN1DDR1ADRA1A | |
| SCHEMBL24463670 | 0.78 | HPGD (0.52) | HPGDMGLLVNN1DDR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118338902-A | Pyrrolo [2,3-b ] pyridine PGDH inhibitors and methods of making and using the same | 埃皮里姆生物股份有限公司 | 2024-07-12 | — | — | CN | disclosed |