Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630162 | 0.81 | — | — | |
| SCHEMBL31599851 | 0.81 | NPC1 (0.31) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15415906 | 0.77 | — | — | |
| SCHEMBL31038498 | 0.74 | ROCK1 (0.34) | KMT2ANPC1RAB9A | |
| SCHEMBL25342261 | 0.73 | KDM4E (0.35) | KDM4EMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19761065 | 0.73 | TLR9 (0.35) | KDM4EMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19761037 | 0.73 | TLR9 (0.34) | KDM4EMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1745767 | 0.73 | MAPT (0.35) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31600741 | 0.71 | CSNK1D (0.33) | KMT2ASMN1; SMN2 | |
| SCHEMBL23828588 | 0.71 | PDE5A (0.40) | KDM4EMAPTKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480039-A | KIF18A inhibitor and preparation method and application thereof | 南京同诺康医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |