SCHEMBL31038579

SCHEMBL31038579

CC1(N)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.79
CNR2 P34972 13/20 0.79
KCNH2 Q12809 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15200804 0.89 CNR1 (1.00) CNR1CNR2KCNH2
SCHEMBL5241718 0.87 CNR1 (0.79) CNR1CNR2KCNH2
SCHEMBL5237529 0.87 CNR1 (0.77) CNR1CNR2KCNH2
SCHEMBL5233969 0.87 CNR1 (0.98) CNR1CNR2KCNH2
SCHEMBL6752816 0.86 CNR1 (0.76) CNR1CNR2KCNH2
SCHEMBL16418418 0.86 CNR1 (1.00) CNR1CNR2KCNH2
SCHEMBL20305056 0.85 CNR1 (0.84) CNR1CNR2KCNH2
SCHEMBL20304618 0.85 CNR1 (1.00) CNR1CNR2KCNH2
SCHEMBL15200957 0.85 CNR1 (0.82) CNR1CNR2KCNH2
SCHEMBL5236621 0.85 CNR1 (0.80) CNR1CNR2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638451-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS AND USES Research Triangle Institute (US) 2025-10-29 EP disclosed
WO-2024134550-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS AND USES RESEARCH TRIANGLE INSTITUTE (US) 2024-06-27 WO disclosed