SCHEMBL31038687

CSCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	4/20	0.57

▸	GLP1R	P43220	1/20	0.56

▸	GCGR	P47871	1/20	0.56

▸	GIPR	P48546	1/20	0.56

▸	PTH1R	Q03431	4/20	0.53

▸	TFPI	P10646	1/20	0.53

▸	VIPR1	P32241	3/20	0.52

▸	VIPR2	P41587	4/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30804674	0.92	BACE1 (0.58)	BACE1GLP1RGCGRGIPRVIPR1
SCHEMBL32670624	0.89	BACE1 (0.61)	BACE1GLP1RGCGRGIPRPTH1R
SCHEMBL30384921	0.89	BACE1 (0.56)	BACE1TFPI
SCHEMBL30431350	0.88	OPRL1 (0.59)	GLP1RGCGRGIPRPTH1RTFPI
SCHEMBL30176500	0.88	VIPR1 (0.64)	BACE1GLP1RGCGRGIPRPTH1R
SCHEMBL30431840	0.88	BACE1 (0.66)	BACE1GLP1RGCGRGIPRPTH1R
SCHEMBL29686720	0.87	BACE1 (0.69)	BACE1GLP1RGCGRGIPRPTH1R
SCHEMBL30429998	0.87	BACE1 (0.52)	BACE1GLP1RGCGRGIPRTFPI
SCHEMBL31182595	0.86	GLP1R (0.68)	GLP1RGCGRGIPRTFPIVIPR1
SCHEMBL31672198	0.86	BACE1 (0.62)	BACE1GLP1RGCGRGIPRTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12060591-B2	Tau protease compositions and methods of use	OLIGOMERIX, INC. (US)	2024-08-13	—	—	US	disclosed