SCHEMBL31039276

SCHEMBL31039276

CCOC(=O)CCc1ccc2c(c1)C(=O)NC2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.50
CYP4A11 Q02928 2/20 0.50
PDE3B Q13370 1/20 0.46
PDE3A Q14432 1/20 0.46
P2RY12 Q9H244 1/20 0.46
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
CLK4 Q9HAZ1 2/20 0.42
DYRK1B Q9Y463 2/20 0.42
FYN P06241 1/20 0.42
CYP4Z1 Q86W10 1/20 0.41
BRD4 O60885 1/20 0.41
NTRK2 Q16620 2/20 0.40
TYRO3 Q06418 1/20 0.40
HRH3 Q9Y5N1 1/20 0.39
APP P05067 1/20 0.39
JAK2 O60674 1/20 0.39
NTRK1 P04629 1/20 0.39
MET P08581 1/20 0.39
FGFR1 P11362 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037780 0.81 NTRK2 (0.49) CLK4DYRK1BFYNNTRK2TYRO3
SCHEMBL31039381 0.76 CYP1A2 (0.46) ALDH1A1GAACLK4DYRK1BFYN
SCHEMBL28513335 0.76 NTRK2 (0.41) CLK4DYRK1BFYNNTRK2TYRO3
SCHEMBL28115873 0.76 NTRK2 (0.49) ALDH1A1GAACLK4DYRK1BFYN
SCHEMBL28243738 0.75 CLK4 (0.45) CLK4DYRK1BFYNNTRK2TYRO3
SCHEMBL8984895 0.75 CYP4F2 (0.61) CYP4F2CYP4A11PDE3BPDE3AP2RY12
SCHEMBL23270115 0.75 CLK4 (0.46) ALDH1A1CLK4DYRK1BFYNNTRK2
SCHEMBL19642067 0.74 CYP4F2 (0.50) CYP4F2CYP4A11PDE3BPDE3AP2RY12
SCHEMBL31680204 0.74 CYP4F2 (0.50) CYP4F2CYP4A11PDE3BPDE3AP2RY12
SCHEMBL7425431 0.74 CYP4F2 (0.47) CYP4F2CYP4A11PDE3BPDE3AP2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655296-A1 CBL-B INHIBITORS Aurigene Oncology Limited (IN) 2025-12-03 EP disclosed
WO-2024156938-A1 CBL-B INHIBITORS ORION CORPORATION (FI) 2024-08-02 WO disclosed