Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.65 |
| ▸ | LCK | P06239 | 18/20 | 0.65 |
| ▸ | BTK | Q06187 | 4/20 | 0.65 |
| ▸ | EGFR | P00533 | 12/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855290 | 1.00 | JAK3 (0.65) | JAK3LCKBTKEGFR | |
| SCHEMBL23484804 | 0.87 | JAK3 (0.49) | JAK3LCKBTKEGFR | |
| Trifluoroacetic Acid SCHEMBL23460049 | 0.83 | JAK3 (0.47) | JAK3LCKBTKEGFR | |
| SCHEMBL31039875 | 0.83 | JAK3 (0.59) | JAK3LCKBTKEGFR | |
| SCHEMBL21855269 | 0.83 | JAK3 (0.59) | JAK3LCKBTKEGFR | |
| SCHEMBL21946750 | 0.82 | BTK (0.40) | JAK3LCKBTKEGFR | |
| SCHEMBL21855214 | 0.82 | JAK3 (0.70) | JAK3LCKBTKEGFR | |
| SCHEMBL21855188 | 0.80 | JAK3 (0.82) | JAK3LCKBTKEGFR | |
| SCHEMBL21946277 | 0.80 | JAK3 (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL31039897 | 0.80 | JAK3 (0.72) | JAK3LCKBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955473-A | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-113412259-B | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-07-16 | — | — | CN | disclosed |