Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.65 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.65 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.60 |
| ▸ | CDK7 | P50613 | 7/20 | 0.60 |
| ▸ | JAK2 | O60674 | 2/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.55 |
| ▸ | CDC7 | O00311 | 2/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627899 | 1.00 | FGFR1 (0.65) | FGFR1FGFR3FGFR2HDAC6CDK7 | |
| SCHEMBL628194 | 0.88 | HDAC6 (0.64) | FGFR1FGFR3FGFR2HDAC6CDK7 | |
| SCHEMBL622021 | 0.88 | FLT3 (0.59) | FGFR1FGFR3FGFR2HDAC6CDK7 | |
| SCHEMBL2144970 | 0.85 | FLT3 (0.55) | FGFR1FGFR3FGFR2HDAC6FLT3 | |
| SCHEMBL627833 | 0.84 | FGFR1 (0.81) | FGFR1FGFR3FGFR2HDAC6CDK7 | |
| SCHEMBL628872 | 0.84 | FGFR1 (0.69) | FGFR1FGFR3FGFR2HDAC6CDK7 | |
| SCHEMBL18812677 | 0.84 | CDK7 (0.63) | FGFR1FGFR3FGFR2HDAC6CDK7 | |
| SCHEMBL627865 | 0.83 | ABCG2 (0.57) | FGFR1FGFR3FGFR2HDAC6CDK2 | |
| SCHEMBL17028029 | 0.83 | FGFR1 (0.48) | FGFR1FGFR3FGFR2HDAC6CDK7 | |
| SCHEMBL761113 | 0.83 | JAK2 (0.62) | FGFR1FGFR3FGFR2HDAC6CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515665-A | Benzamidoazaindole derivatives, methods of preparation, compositions comprising the same and uses thereof | 哈尔滨医科大学 | 2024-08-20 | — | — | CN | claimed |
| CN-118515665-A | Benzamidoazaindole derivatives, methods of preparation, compositions comprising the same and uses thereof | 哈尔滨医科大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-118515665-A | Benzamidoazaindole derivatives, methods of preparation, compositions comprising the same and uses thereof | 哈尔滨医科大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-118515665-A | Benzamidoazaindole derivatives, methods of preparation, compositions comprising the same and uses thereof | 哈尔滨医科大学 | 2024-08-20 | — | — | CN | disclosed |