Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 10/20 | 0.55 |
| ▸ | GRM1 | Q13255 | 10/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.47 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17001926 | 1.00 | PDK4 (0.59) | PDK4PDE10AGRM5GRM1HTR6 | |
| SCHEMBL4013425 | 0.90 | PDE10A (0.62) | PDK4PDE10AGRM5GRM1HTR6 | |
| SCHEMBL25345866 | 0.89 | PDE10A (0.49) | PDK4PDE10AGRM5GRM1NAMPT | |
| SCHEMBL31155284 | 0.89 | PDE10A (0.49) | PDK4PDE10AGRM5GRM1NAMPT | |
| SCHEMBL13769826 | 0.87 | PDE10A (0.69) | PDK4PDE10AGRM5GRM1HTR6 | |
| SCHEMBL17655532 | 0.86 | PDK4 (0.61) | PDK4PDE10AGRM5GRM1HTR6 | |
| SCHEMBL13770040 | 0.86 | PDE10A (0.60) | PDK4PDE10AGRM5GRM1HTR6 | |
| SCHEMBL15951022 | 0.85 | PDK4 (0.60) | PDK4PDE10AGRM5GRM1HTR6 | |
| SCHEMBL30676170 | 0.85 | GRM5 (0.61) | PDK4PDE10AGRM5GRM1HTR6 | |
| SCHEMBL2631187 | 0.85 | GRM5 (0.61) | PDK4PDE10AGRM5GRM1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714446-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2026-03-25 | — | — | EP | disclosed |
| EP-4413985-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2024-08-14 | — | — | EP | disclosed |