Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16992360 | 0.89 | CHRM4 (0.51) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL16992430 | 0.89 | CHRM4 (0.51) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL20909164 | 0.88 | CHRM4 (0.53) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL16992560 | 0.88 | CHRM4 (0.53) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL18923702 | 0.86 | CHRM4 (0.49) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL16992436 | 0.86 | CHRM4 (0.49) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL16992448 | 0.86 | CHRM4 (0.49) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL16992449 | 0.86 | CHRM4 (0.49) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL16992364 | 0.86 | CHRM4 (0.52) | CHRM4CHRM2CHRM1TP53TDP1 | |
| SCHEMBL16992049 | 0.85 | CHRM4 (0.47) | CHRM4CHRM2CHRM1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714446-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2026-03-25 | — | — | EP | disclosed |
| EP-4413985-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2024-08-14 | — | — | EP | disclosed |