Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25235268 | 1.00 | BACE1 (0.50) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL22912731 | 0.88 | BACE1 (0.52) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30212537 | 0.88 | BACE1 (0.52) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30297083 | 0.87 | NR1H2 (0.49) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL24157379 | 0.87 | NR1H2 (0.49) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL24156519 | 0.85 | BACE1 (0.49) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30212542 | 0.85 | BACE1 (0.49) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL29221502 | 0.85 | BACE1 (0.47) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27202606 | 0.84 | CKS1B (0.49) | BACE1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL25234852 | 0.84 | BACE1 (0.48) | BACE1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696036-A | PARP1 inhibitors | 突触活化疗法股份有限公司 | 2024-09-24 | — | — | CN | disclosed |