SCHEMBL31043443

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.63

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	7/20	0.59

▸	NPY4R	P50391	7/20	0.59

▸	NPY5R	Q15761	7/20	0.59

▸	NPY1R	P25929	5/20	0.59

▸	EP300	Q09472	1/20	0.58

▸	HIF1A	Q16665	1/20	0.58

▸	MAPK8	P45983	1/20	0.57

▸	MAPK9	P45984	1/20	0.57

▸	MAPK10	P53779	1/20	0.57

▸	CALCR	P30988	8/20	0.57

▸	RAMP3	O60896	4/20	0.57

▸	CXCR4	P61073	2/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30726569	0.91	RAMP3 (0.63)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30658199	0.90	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL29827221	0.90	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30262203	0.90	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL29786933	0.90	RAMP3 (0.57)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL29357279	0.90	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL29456236	0.89	EP300 (0.53)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31182614	0.89	MAPK8 (0.61)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30429252	0.89	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30495693	0.89	MAPK8 (0.61)	NPY2RNPY4RNPY5RNPY1REP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240269300-A1	METHODS OF USING GLYCOPOLYSIALYLATED THERAPEUTIC PROTEINS	XENETIC BIOSCIENCES, INC. (US)	2024-08-15	—	—	US	disclosed