Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185073 | 1.00 | ACE (0.39) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL3091008 | 1.00 | ACE (0.39) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL22861384 | 1.00 | ACE (0.39) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL17856804 | 1.00 | ACE (0.39) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL2184116 | 1.00 | ACE (0.39) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL25019185 | 1.00 | ACE (0.39) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL10306747 | 1.00 | ACE (0.39) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL2184849 | 0.82 | GABRR1 (0.42) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL2182349 | 0.82 | GABRR1 (0.42) | ACEAKR1C3AKR1C1GABRR1PLG | |
| SCHEMBL3104619 | 0.82 | GABRR1 (0.42) | ACEAKR1C3AKR1C1GABRR1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803808-B2 | Production of polyketides and other natural products | WYETH LLC (US) | 2010-09-28 | — | — | US | disclosed |
| US-20090253732-A1 | Production Of Polyketides And Other Natural Products | BIOTICA TECHNOLOGY LIMITED | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253732-A1 | Production Of Polyketides And Other Natural Products | PBK, IL15, IL17A | ACE 3938/4885AKR1C3 154/4885AKR1C1 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.