SCHEMBL31046884

SCHEMBL31046884

O=C(NC12CC(C(F)(F)F)(C1)C2)c1ccc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 4/20 0.50
▸ ACLY P53396 2/20 0.47
▸ USP2 O75604 4/20 0.46
▸ USP8 P40818 4/20 0.46
▸ USP36 Q9P275 1/20 0.44
▸ DNMT1 P26358 1/20 0.42
▸ CASP6 P55212 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ GPR27 Q9NS67 4/20 0.41
▸ AVPR2 P30518 3/20 0.41
▸ LMNA P02545 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ CCR1 P32246 1/20 0.41
▸ CCR2 P41597 1/20 0.41
▸ FLT1 P17948 1/20 0.40
▸ FLT4 P35916 1/20 0.40
▸ KDR P35968 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23877472 1.00 KDM1A (0.50) KDM1AACLYUSP2USP8USP36
SCHEMBL23879636 0.92 KDM1A (0.50) KDM1AACLYUSP2USP8USP36
SCHEMBL23877433 0.91 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL29460280 0.91 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL29460221 0.91 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL23877599 0.91 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL23877473 0.91 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL23877474 0.91 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL23877479 0.91 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL30547611 0.91 KDM1A (0.49) KDM1AACLYUSP2USP8USP36

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791407-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-10-18 — — CN disclosed
CN-118638096-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-09-13 — — CN disclosed
CN-112204008-B Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives 奥索生物公司 2024-07-05 — — CN disclosed
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