Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.36 |
| ▸ | SYK | P43405 | 5/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899919 | 0.96 | HRH3 (0.38) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL30899857 | 0.94 | SYK (0.39) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL30899931 | 0.92 | HRH3 (0.38) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL31047542 | 0.91 | HRH3 (0.38) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL30899916 | 0.90 | CDK4 (0.38) | HRH3ALDH1A1ALKSYKPDE7A | |
| SCHEMBL30899876 | 0.85 | HRH3 (0.42) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL30899930 | 0.84 | HRH3 (0.41) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL30899860 | 0.83 | HRH3 (0.39) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL31047587 | 0.82 | HRH3 (0.40) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL30899887 | 0.79 | SYK (0.44) | HRH3KDM4EALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163380-A1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |