Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639251 | 0.84 | SERPINE1 (0.46) | SERPINE1TNKSWNT3ATNKS2PARP1 | |
| SCHEMBL28738728 | 0.84 | SERPINE1 (0.46) | SERPINE1TNKSWNT3ATNKS2PARP1 | |
| SCHEMBL29639232 | 0.82 | TNKS (0.44) | SERPINE1TNKSWNT3ATNKS2PARP1 | |
| SCHEMBL31047692 | 0.81 | SERPINE1 (0.51) | SERPINE1TNKSTNKS2PARP1PARP2 | |
| SCHEMBL31047691 | 0.81 | SERPINE1 (0.51) | SERPINE1TNKSTNKS2PARP1KDM4E | |
| SCHEMBL31047690 | 0.80 | SERPINE1 (0.50) | SERPINE1TNKSTNKS2PARP1KDM4E | |
| SCHEMBL31047669 | 0.78 | SERPINE1 (0.65) | SERPINE1TNKSTNKS2PARP1KDM4E | |
| SCHEMBL31047687 | 0.78 | SERPINE1 (0.51) | SERPINE1PARP1KDM4EMEN1KMT2A | |
| SCHEMBL31047672 | 0.78 | SERPINE1 (0.49) | SERPINE1TNKSTNKS2PARP1KDM4E | |
| SCHEMBL31047680 | 0.75 | SERPINE1 (0.54) | SERPINE1TNKSTNKS2PARP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496146-A | Preparation method of isoindoline diketone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |