Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.69 |
| ▸ | TNKS | O95271 | 5/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047682 | 0.86 | SERPINE1 (0.51) | SERPINE1TNKSTNKS2PARP2PARP1 | |
| SCHEMBL31047669 | 0.86 | SERPINE1 (0.65) | SERPINE1TNKSTNKS2PARP1KDM4E | |
| SCHEMBL31047681 | 0.85 | SERPINE1 (0.50) | SERPINE1TNKSTNKS2PARP1KDM4E | |
| SCHEMBL31047696 | 0.83 | SERPINE1 (0.69) | SERPINE1TNKSTNKS2PARP2PARP1 | |
| SCHEMBL31047695 | 0.83 | PARP1 (0.49) | SERPINE1TNKSTNKS2PARP1CTSV | |
| SCHEMBL31047692 | 0.83 | SERPINE1 (0.51) | SERPINE1TNKSTNKS2PARP2PARP1 | |
| SCHEMBL29639170 | 0.81 | SERPINE1 (0.71) | SERPINE1TNKSTNKS2PARP2PARP1 | |
| SCHEMBL29031884 | 0.81 | SERPINE1 (0.71) | SERPINE1TNKSTNKS2PARP2PARP1 | |
| SCHEMBL31047675 | 0.80 | SERPINE1 (0.49) | SERPINE1TNKSTNKS2PARP1MEN1 | |
| SCHEMBL31047683 | 0.80 | TNKS (0.52) | SERPINE1TNKSTNKS2PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496146-A | Preparation method of isoindoline diketone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |