SCHEMBL31048243

SCHEMBL31048243

CON(C)C(=O)[C@@H]1CCCCCN1C(=O)OC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.48
USP30 Q70CQ3 6/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.42
LMNA P02545 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
UCHL1 P09936 3/20 0.41
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1257155 0.99 HSD17B10 (0.49) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL1250737 0.99 HSD17B10 (0.49) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL5328715 0.99 HSD17B10 (0.49) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL25395953 0.94 HSD17B10 (0.53) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL1584759 0.94 HSD17B10 (0.53) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL903492 0.94 HSD17B10 (0.53) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL1256351 0.94 HSD17B10 (0.53) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL2096289 0.89 HSD17B10 (0.43) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL444365 0.89 HSD17B10 (0.43) HSD17B10USP30SMN1; SMN2NPC1LMNA
SCHEMBL25701906 0.89 HSD17B10 (0.43) HSD17B10USP30SMN1; SMN2NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024178304-A1 KRAS MODULATORS ALTEROME THERAPEUTICS, INC. (US) 2024-08-29 WO disclosed