Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132570 | 0.87 | PPARA (0.65) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL212797 | 0.87 | PPARA (0.65) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL212796 | 0.87 | PPARA (0.65) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL35211707 | 0.85 | PPARA (0.59) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL1363391 | 0.85 | PPARA (0.59) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL31048314 | 0.85 | PPARA (0.62) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL1569316 | 0.85 | PPARA (0.59) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL31048196 | 0.83 | PPARA (0.52) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL18407225 | 0.83 | PPARA (0.69) | PPARAATMSYKCTSSPPARG | |
| SCHEMBL13040196 | 0.82 | PPARA (0.56) | PPARAATMSYKCTSSPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178304-A1 | KRAS MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-08-29 | — | — | WO | disclosed |