Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 3/20 | 0.32 |
| ▸ | RAF1 | P04049 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31048938 | 0.91 | KRAS (0.39) | GPR119HDAC1KRASRAF1GRM2 | |
| SCHEMBL31049047 | 0.87 | JAK1 (0.34) | GPR119KRAS | |
| SCHEMBL31048893 | 0.85 | JAK1 (0.35) | GPR119HDAC1KRAS | |
| SCHEMBL31049034 | 0.85 | — | — | |
| SCHEMBL31048939 | 0.85 | JAK1 (0.35) | GPR119HDAC1KRAS | |
| SCHEMBL31049089 | 0.85 | JAK1 (0.35) | GPR119HDAC1KRAS | |
| SCHEMBL31048942 | 0.85 | JAK1 (0.35) | GPR119HDAC1KRAS | |
| SCHEMBL31049212 | 0.85 | JAK1 (0.35) | GPR119HDAC1KRAS | |
| SCHEMBL31049162 | 0.84 | ALOX5AP (0.30) | — | |
| SCHEMBL31048982 | 0.84 | JAK1 (0.35) | GPR119KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024167922-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-08-15 | — | — | WO | disclosed |