⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184 | 1.00 | — | — | |
| SCHEMBL9731838 | 0.94 | TSHR (0.50) | — | |
| SCHEMBL28868012 | 0.94 | — | — | |
| Water SCHEMBL8946414 | 0.94 | — | — | |
| Fluoride SCHEMBL8459296 | 0.94 | — | — | |
| SCHEMBL27944 | 0.88 | — | — | |
| SCHEMBL8718302 | 0.88 | — | — | |
| SCHEMBL1039462 | 0.88 | — | — | |
| Chloropentafluoroethane SCHEMBL9349278 | 0.85 | TSHR (0.42) | — | |
| Fluoride SCHEMBL8853743 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803956-B2 | Benzofuran derivatives useful for treating hyper-proliferative disorders | BAYER PHARMACEUTICALS CORPORATION (US) | 2010-09-28 | — | — | US | disclosed |
| US-7659412-B2 | Benzofuran derivatives useful for treating hyper-proliferative disorders | BAYER HEALTHCARE LLC (US) | 2010-02-09 | — | — | US | disclosed |
| US-20090292014-A1 | BENZOFURAN DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | ZHANG CHENGZHI | 2009-11-26 | — | — | US | disclosed |
| US-7563893-B2 | 3-Phenyl-cinnoline analogue and antitumor agent using the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-07-21 | — | — | US | disclosed |
| US-20090023783-A1 | BENZOFURAN DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | ZHANG CHENGZHI | 2009-01-22 | — | — | US | disclosed |
| US-7420066-B2 | Benzofuran derivatives useful for treating hyper-proliferative disorders | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-09-02 | — | — | US | disclosed |
| US-20060194816-A1 | Benzofuran derivatives useful for treating hyper-proliferative disorders | BAER PHAMACEUTICALS CORPORATION (US) | 2006-08-31 | — | — | US | disclosed |
| EP-1654245-A1 | BENZOFURAN DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | Bayer Pharmaceuticals Corporation (US) | 2006-05-10 | — | — | EP | disclosed |
| US-20060058305-A1 | 3-Phenyl-cinnoline homologue and antitumor agent containing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1571148-A1 | 3-PHENYL-CINNOLINE HOMOLOGUE AND ANTITUMOR AGENT CONTAINING THE SAME | Nippon Kayaku Kabushiki Kaisha (JP) | 2005-09-07 | — | — | EP | disclosed |
| WO-2005014566-A1 | BENZOFURAN DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-02-17 | — | — | WO | disclosed |