SCHEMBL31049465

SCHEMBL31049465

COC[C@H]1CN(c2cc(S(=O)(=O)NC3(C)CC3)cn3c(-c4nnc(C(F)F)o4)cnc23)[C@@H](C)CO1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 12/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31049454 0.88 PARG (0.41) PARG
SCHEMBL31049307 0.85 PARG (0.39) PARG
SCHEMBL31049476 0.83 PARG (0.35) PARG
SCHEMBL31049425 0.81 PARG (0.36) PARG
SCHEMBL31049582 0.81 PARG (0.36) PARG
SCHEMBL31049604 0.80 PARG (0.42) PARG
SCHEMBL31049317 0.80 PARG (0.37) PARG
SCHEMBL31049310 0.78 PARG (0.38) PARG
SCHEMBL31049340 0.78 PARG (0.38) PARG
SCHEMBL31049451 0.78 PARG (0.45) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173453-A1 HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS IDEAYA BIOSCIENCES, INC. (US) 2024-08-22 WO disclosed