SCHEMBL31049539

SCHEMBL31049539

COC[C@H]1CN(c2cc(S(=O)(=O)NC3(C#N)CC3)cn3c(-c4nnc(C(F)F)s4)cnc23)[C@@H](C)CO1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31049621 1.00 PARG (0.43) PARG
SCHEMBL31049540 0.93 PARG (0.41) PARG
SCHEMBL31049477 0.93 PARG (0.40) PARG
SCHEMBL31049586 0.93 PARG (0.40) PARG
SCHEMBL31049485 0.90 PARG (0.41) PARG
SCHEMBL31049411 0.89 PARG (0.44) PARG
SCHEMBL31049425 0.88 PARG (0.36) PARG
SCHEMBL31049582 0.88 PARG (0.36) PARG
SCHEMBL31049508 0.86 PARG (0.38) PARG
SCHEMBL31049554 0.86 PARG (0.38) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173453-A1 HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS IDEAYA BIOSCIENCES, INC. (US) 2024-08-22 WO disclosed