Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.47 |
| ▸ | VEGFA | P15692 | 5/20 | 0.46 |
| ▸ | FLT1 | P17948 | 5/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25232060 | 1.00 | EGLN1 (0.47) | EGLN1VEGFAFLT1EGLN3NPC1 | |
| SCHEMBL25228382 | 0.89 | EGLN1 (0.52) | EGLN1VEGFAFLT1EGLN3FTO | |
| SCHEMBL25276450 | 0.79 | MEN1 (0.49) | EGLN1VEGFAFLT1EGLN3NPC1 | |
| SCHEMBL30457571 | 0.79 | EGLN1 (0.54) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL31050993 | 0.79 | EGLN1 (0.54) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL25233766 | 0.79 | EGLN1 (0.54) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL25285450 | 0.78 | EGLN1 (0.52) | EGLN1VEGFAFLT1EGLN3FTO | |
| SCHEMBL25280768 | 0.78 | EGLN1 (0.57) | EGLN1VEGFAFLT1EGLN3FTO | |
| SCHEMBL25284922 | 0.78 | EGLN1 (0.45) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL25422719 | 0.77 | EGLN1 (0.53) | EGLN1VEGFAFLT1EGLN3FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715015-A | Selective PHD1 inhibitor compounds, compositions and methods of use | 阿克比治疗有限公司 | 2024-09-27 | — | — | CN | disclosed |