Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 12/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052554 | 0.90 | LCK (0.41) | LCKMEN1POLBKMT2AMAPK14 | |
| SCHEMBL31052563 | 0.85 | LCK (0.40) | LCKMAPK14NPC1RAB9AMAPK13 | |
| SCHEMBL31052681 | 0.80 | LCK (0.60) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052442 | 0.78 | LCK (0.44) | LCKMAPK14NPC1RAB9AMAPK13 | |
| SCHEMBL31052435 | 0.78 | LCK (0.38) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052656 | 0.77 | PDE4D (0.41) | LCKMEN1POLBKMT2AMAPK14 | |
| SCHEMBL31052458 | 0.77 | KCNQ3 (0.42) | MEN1POLBKMT2ANPC1RAB9A | |
| SCHEMBL31704595 | 0.77 | KDM4E (0.42) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL23888273 | 0.76 | CYP1A2 (0.43) | MEN1POLBKMT2ANPC1RAB9A | |
| SCHEMBL31705616 | 0.76 | LCK (0.48) | LCKMAPK14MAPK13EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676923-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | Cancer Research Technology Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184550-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |