Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 16/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | HCK | P08631 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | FGR | P09769 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052523 | 0.88 | LCK (0.46) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052645 | 0.88 | LCK (0.46) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052617 | 0.79 | LCK (0.46) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052727 | 0.79 | LCK (0.50) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31704600 | 0.79 | LCK (0.51) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052513 | 0.79 | LCK (0.50) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31705253 | 0.79 | LCK (0.51) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052676 | 0.76 | MAPK14 (0.55) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052442 | 0.74 | LCK (0.44) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052616 | 0.73 | MAPK14 (0.47) | LCKMAPK14MAPK13EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676923-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | Cancer Research Technology Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184550-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |