Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 15/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | HCK | P08631 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704661 | 0.87 | LCK (0.47) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31705212 | 0.87 | MAPK14 (0.41) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31704600 | 0.85 | LCK (0.51) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31705253 | 0.85 | LCK (0.51) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052513 | 0.83 | LCK (0.50) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052669 | 0.83 | LCK (0.44) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31052538 | 0.83 | MAPK14 (0.49) | LCKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL31704460 | 0.83 | LCK (0.51) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL14568768 | 0.82 | LCK (0.65) | LCK | |
| SCHEMBL7198114 | 0.82 | LCK (0.69) | LCKMAPK14MAPK13EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676923-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | Cancer Research Technology Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184550-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |