Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.42 |
| ▸ | LCK | P06239 | 15/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | FGR | P09769 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052493 | 0.89 | LCK (0.39) | MAPK14LCKAURKAAURKBMAPK13 | |
| SCHEMBL31052502 | 0.88 | MAPK14 (0.39) | MAPK14LCKMAPK13ABL1EGFR | |
| SCHEMBL31052634 | 0.87 | LCK (0.38) | MAPK14LCKAURKAAURKBMAPK13 | |
| SCHEMBL31052569 | 0.86 | LCK (0.46) | MAPK14LCKMAPK13ABL1EGFR | |
| SCHEMBL31052604 | 0.86 | LCK (0.37) | MAPK14LCKAURKAAURKBMAPK13 | |
| SCHEMBL31052666 | 0.84 | MAPK14 (0.42) | MAPK14LCKMAPK13ABL1EGFR | |
| SCHEMBL31052568 | 0.83 | LCK (0.45) | MAPK14LCKMAPK13ABL1EGFR | |
| SCHEMBL31052627 | 0.82 | MAPK14 (0.40) | MAPK14LCKAURKAAURKBMAPK13 | |
| SCHEMBL31105857 | 0.81 | MAPK14 (0.41) | MAPK14LCKMAPK13ABL1EGFR | |
| SCHEMBL31052617 | 0.81 | LCK (0.46) | MAPK14LCKMAPK13ABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676923-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | Cancer Research Technology Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184550-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |