Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.58 |
| ▸ | GRM5 | P41594 | 11/20 | 0.58 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936899 | 0.84 | GRM1 (0.55) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL30308912 | 0.82 | GRM1 (0.64) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL31227002 | 0.81 | GRM1 (0.69) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL28672701 | 0.81 | JMJD6 (0.41) | GRM1GRM5 | |
| SCHEMBL31053177 | 0.81 | GRM1 (0.53) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL29946045 | 0.80 | GRM1 (0.56) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL25723283 | 0.80 | GRM1 (0.46) | GRM1GRM5PDK4HTR6JAK1 | |
| SCHEMBL4251822 | 0.79 | GRM5 (0.70) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL29559340 | 0.79 | GRM5 (0.70) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL2891208 | 0.79 | GRM1 (0.54) | GRM1GRM5PDK4NAMPTJAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025066935-A1 | COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2025-04-03 | — | — | WO | disclosed |
| CN-113735825-B | 1,2,3, 6-Tetrahydropyridine compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2024-08-27 | — | — | CN | disclosed |