Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429997 | 1.00 | MYC (0.40) | MYCPOLBHDAC3HDAC1HDAC11 | |
| SCHEMBL25342713 | 0.89 | MYC (0.35) | MYCGSTP1GSTM2KCNH2 | |
| SCHEMBL30520943 | 0.89 | MYC (0.35) | MYCGSTP1GSTM2KCNH2 | |
| SCHEMBL25343085 | 0.82 | KCNH2 (0.35) | MYCGSTP1GSTM2KCNH2ALDH1A1 | |
| SCHEMBL30520910 | 0.82 | KCNH2 (0.37) | MYCGSTP1GSTM2KCNH2ALDH1A1 | |
| SCHEMBL25342882 | 0.82 | KCNH2 (0.37) | MYCGSTP1GSTM2KCNH2ALDH1A1 | |
| SCHEMBL30521024 | 0.82 | KCNH2 (0.35) | MYCGSTP1GSTM2KCNH2ALDH1A1 | |
| SCHEMBL30520753 | 0.77 | IDO1 (0.34) | MYCKCNH2ALDH1A1HPGD | |
| SCHEMBL25342557 | 0.77 | IDO1 (0.34) | MYCKCNH2ALDH1A1HPGD | |
| SCHEMBL31054006 | 0.74 | GSTP1 (0.53) | MYCGSTP1GSTM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574822-A | Novel PROTAC compounds | 甘李药业股份有限公司 | 2024-08-30 | — | — | CN | disclosed |