Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810499 | 1.00 | TSHR (0.71) | TSHRACHEHSD17B10CYP19A1ALDH1A1 | |
| Fluoride SCHEMBL27948299 | 0.98 | TSHR (0.68) | TSHRACHEHSD17B10CYP19A1ALDH1A1 | |
| SCHEMBL219410 | 0.84 | CYP19A1 (0.55) | TSHRCYP19A1ALDH1A1CYP3A4ESPL1 | |
| SCHEMBL1026447 | 0.84 | CYP19A1 (0.62) | TSHRCYP19A1ALDH1A1CYP3A4ESPL1 | |
| SCHEMBL1097495 | 0.84 | TSHR (1.00) | TSHRACHEHSD17B10CYP19A1ALDH1A1 | |
| SCHEMBL635130 | 0.84 | TSHR (0.90) | TSHRACHEHSD17B10CYP19A1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27814867 | 0.82 | TSHR (0.49) | TSHRACHEHSD17B10CYP19A1ALDH1A1 | |
| Nitrogen SCHEMBL27917117 | 0.79 | CYP19A1 (0.56) | TSHRCYP19A1ALDH1A1CYP3A4ESPL1 | |
| Benzene SCHEMBL27782128 | 0.79 | CYP19A1 (0.56) | TSHRCYP19A1ALDH1A1CYP3A4ESPL1 | |
| SCHEMBL19026582 | 0.77 | CYP19A1 (0.68) | TSHRCYP19A1ALDH1A1CYP3A4ESPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459440-A | Preparation method and application of tetra-substituted aryl compound | 江苏普莱医药生物技术有限公司 | 2024-08-09 | — | — | CN | disclosed |