(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL3105583

C(=C/c1ccccc1)\c1ccccc1.[NaH].[NaH]

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.69
NFE2L2 Q16236 4/20 0.63
CYP19A1 P11511 2/20 0.63
MAOA P21397 2/20 0.63
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
CHAT P28329 2/20 0.57
TRPA1 O75762 3/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
ALOX5 P09917 1/20 0.55
MAPK1 P28482 1/20 0.55
RELA Q04206 2/20 0.55
CYP11B1 P15538 1/20 0.55
CYP11B2 P19099 1/20 0.55
HDAC3 O15379 1/20 0.52
TNKS O95271 1/20 0.52
HDAC4 P56524 1/20 0.52
HDAC1 Q13547 1/20 0.52
HCAR2 Q8TDS4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL11350623 1.00 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL3105585 1.00 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL11350626 1.00 MAOB (0.69) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL443 0.96 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL21847984 0.96 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL347707 0.96 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.96 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL22712863 0.96 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL9134296 0.96 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1
(Z)-1,2-Diphenylethene SCHEMBL9488270 0.96 MAOB (0.73) MAOBNFE2L2CYP19A1MAOAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710753-B Washable heat and plasma resistant coating for laser applications 约翰·克莱昂·摩尔 2023-09-19 CN claimed
US-3965206-A Production of stilbene and styrene MONSANTO COMPANY (US) 1976-06-22 US claimed
CN-117794504-A Iris root extract, compositions and methods for dermatological use 捷通国际有限公司 2024-03-29 CN disclosed
US-7803747-B2 Detergent composition for halogenated dry cleaning solvents ENVIRO TECH INTERNATIONAL, INC. (US) 2010-09-28 US disclosed
WO-2008137277-A1 DETERGENT COMPOSITION FOR HALOGENATED DRY CLEANING SOLVENTS ENVIRO TECH INTERNATIONAL, INC. (US) 2008-11-13 WO disclosed
US-20080274935-A1 Detergent Composition for Halogenated Dry Cleaning Solvents ENVIRO TECH INTERNATIONAL, INC. (US) 2008-11-06 US disclosed
CN-1084211-A The dye transfer inhibiting composition that contains tensio-active agent PROCTER & GAMBLE (NL) 1994-03-23 CN disclosed
US-4117021-A PROCESS FOR REMOVING ORGANIC OXYGEN-CONTAINING IMPURITIES FROM AN ORGANIC COMPOSITION GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-09-26 US disclosed
US-4104318-A Process for removing organic oxygen-containing impurities from an organic composition in the presence of steam GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-08-01 US disclosed
US-3965206-A Production of stilbene and styrene MONSANTO COMPANY (US) 1976-06-22 US disclosed