Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055924 | 0.85 | NPC1 (0.38) | NPC1SMN1; SMN2ALDH1A1RXFP1TSHR | |
| SCHEMBL31056015 | 0.83 | NPC1 (0.36) | NPC1NPSR1ADORA2AADORA2B | |
| SCHEMBL23827125 | 0.74 | GAA (0.36) | NPC1SMN1; SMN2MAPK10GAAKMT2A | |
| SCHEMBL31336366 | 0.74 | GAA (0.36) | NPC1SMN1; SMN2MAPK10GAAKMT2A | |
| SCHEMBL31300570 | 0.74 | NPC1 (0.38) | NPC1SMN1; SMN2ALDH1A1MAPK10CYP1A2 | |
| SCHEMBL20605036 | 0.74 | NPC1 (0.38) | NPC1SMN1; SMN2ALDH1A1MAPK10CYP1A2 | |
| SCHEMBL18304450 | 0.73 | MAPK10 (0.56) | SMN1; SMN2ALDH1A1MAPK10CYP1A2CYP2C9 | |
| SCHEMBL31129559 | 0.72 | NPC1 (0.33) | NPC1 | |
| SCHEMBL24607455 | 0.72 | NPC1 (0.35) | NPC1KMT2ATSHRHSD17B10 | |
| SCHEMBL31638716 | 0.72 | NPC1 (0.41) | NPC1ALDH1A1GAAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |