Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124004 | 1.00 | ERN1 (0.39) | ERN1MAP4K4AGBL2CHEK2HCAR2 | |
| SCHEMBL2123346 | 0.79 | MAP4K4 (0.31) | MAP4K4AGBL2HTTKMT2ANOS3 | |
| SCHEMBL29954200 | 0.78 | ERN1 (0.42) | ERN1AGBL2HCAR2ALDH1A1 | |
| SCHEMBL2561425 | 0.78 | MAP4K4 (0.51) | ERN1MAP4K4CHEK2ALDH1A1 | |
| SCHEMBL29955302 | 0.76 | ERN1 (0.34) | ERN1MAP4K4ALOX5APFEN1VRK1 | |
| SCHEMBL20874412 | 0.76 | MIF (0.44) | MAP4K4AGBL2HCAR2HTTALDH1A1 | |
| SCHEMBL2556015 | 0.76 | CHEK2 (0.52) | MAP4K4CHEK2KMT2A | |
| SCHEMBL24609208 | 0.75 | HTT (0.30) | HTTKMT2ANOS3NOS1NOS2 | |
| SCHEMBL124567 | 0.75 | KMT2A (0.54) | ERN1MAP4K4HTTKMT2AALDH1A1 | |
| SCHEMBL247814 | 0.75 | ERN1 (0.39) | ERN1HTTKMT2ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |