Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31056645 | 0.99 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL31056469 | 0.82 | TMEM97 (0.44) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL4781078 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL31269614 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL31056541 | 0.81 | TMEM97 (0.44) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL7802330 | 0.80 | HTR2C (0.55) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL31056879 | 0.80 | TMEM97 (0.44) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL20299628 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL1673785 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9APDE4BHTT | |
| SCHEMBL24835123 | 0.78 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |